STAT5B Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 51072-2-AP

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Freight/Packing

Con: 22 μg/150 μl

Choose size:

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Species specificity:
human

Positive WB detected in:
K-562 cells

Recommended dilution:
WB : 1:500-1:3000

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
signal transducer and activator of transcription 5B

Calculated molecular weight:
90 kDa

Observed molecular weight:
90 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
STAT5B

Synonyms
STAT5, STAT5B, STAT5B-Specific
Background

STAT5B belongs to the transcription factor STAT family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B carries out a dual function: signal transduction and activation of transcription. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This antibody is specific to STAT5B. It has no cross reaction to STAT5A.


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