STAT5B Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66427-1-Ig |CloneNo.: 1D9B11

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Freight/Packing

Con: 150 μg/150 μl

Choose size:

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Species specificity:
human

Positive WB detected in:
Jurkat cells, HEK-293 cells

Recommended dilution:
WB : 1:5000-1:50000

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
signal transducer and activator of transcription 5B

Calculated molecular weight:
787aa,90 kDa

Observed molecular weight:
90 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
STAT5B

Synonyms
STAT5, STAT5B
Background

STAT5B belongs to the transcription factor STAT family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT5B carries out a dual function: signal transduction and activation of transcription. STAT5B mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression.


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