STRA6 Polyclonal antibody

STRA6 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse and More (1)

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 22001-1-AP

Synonyms

MCOPS9, PP14296, STRA6, UNQ3126/PRO10282/PRO19578



Tested Applications

Positive WB detected inmouse kidney tissue, rat kidney tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

22001-1-AP targets STRA6 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen STRA6 fusion protein Ag17591
Full Name stimulated by retinoic acid gene 6 homolog (mouse)
Calculated Molecular Weight 667 aa, 74 kDa
Observed Molecular Weight 73-78 kDa
GenBank Accession NumberBC025256
Gene Symbol STRA6
Gene ID (NCBI) 64220
RRIDAB_11064606
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

STRA6, also known as MCOPS9 and PP14296. Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin. (PMID:9452451; 18316031; 22665496; 21368206; 22665496).

Protocols

Product Specific Protocols
WB protocol for STRA6 antibody 22001-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseIF,WB

Int J Mol Sci

Retinoid Regulation of Ocular Surface Innate Inflammation.

Authors - Jehan Alam
humanIF

Sci Rep

TDP-43 aggregation mirrors TDP-43 knockdown, affecting the expression levels of a common set of proteins.

Authors - S Prpar Mihevc
humanIF

Endocrinology

De novo-synthesized retinoic acid in ovarian antral follicles enhances FSH-mediated ovarian follicular cell differentiation and female fertility.

Authors - Tomoko Kawai
mouseIHC

Lab Invest

Nuclear receptor binding factor 2 (NRBF2) is required for learning and memory.

Authors - Xiaosen Ouyang
ratWB

eNeuro

Differential Retinoic Acid Signaling in the Hippocampus of Aged Rats with and without Memory Impairment.

Authors - Marta U Wołoszynowska-Fraser
mouseWB

J Food Biochem

Inhibitory effect of chitooligosaccharides on retinol metabolism and bioavailability in mice.

Authors - Wei Li

Reviews

The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


FH

Christian (Verified Customer) (02-19-2020)

The antibody works quite well, not many unspecific bands.

  • Applications: Western Blot,
  • Cell Tissue Type: HUVEC