TCN2 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 12157-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human, mouse, rat, cat, dog

Positive WB detected in:
A375 cells, mouse small intestine tissue, rat liver tissue, Transfected HEK-293 cells

Positive IHC detected in:
human lung cancer tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
transcobalamin II; macrocytic anemia

Calculated molecular weight:
400aa,44 kDa

Observed molecular weight:
48kd

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TCN2

Synonyms
D22S676, D22S750, TC 2, TC II, TC2, TCII, TCN2, Transcobalamin 2, Transcobalamin II
Background

TCN2 (Transcobalamin-2) is a vitamin B12 (cobalamin; Cbl) binding and transport protein in plasma that facilitates the cellular uptake of the vitamin. TCN2 is secreted in a constitutive fashion in most cells. Plasma TCN2 levels have been reported to be elevated in a number of diverse human diseases. Defects in TCN2 are cause of transcobalamin-2 deficiency. (10714245)


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