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THOC3 Polyclonal antibody

THOC3 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 11716-1-AP

Synonyms

hTREX45, TEX1, TEX1 homolog, THO complex 3, THO complex subunit 3, Tho3, THOC3

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using THOC3 Polyclonal antibody (11716-1-AP)

    WB analysis using 11716-1-AP

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 11716-1-AP (THOC3 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

Tested Applications

Positive WB detected inHEK-293 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

11716-1-AP targets THOC3 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen THOC3 fusion protein Ag2289
Full Name THO complex 3
Calculated Molecular Weight 327 aa, 36 kDa
Observed Molecular Weight39 kDa
GenBank Accession NumberBC006849
Gene Symbol THOC3
Gene ID (NCBI) 84321
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

THOC3 is a component of the nuclear THO transcription elongation complex, which is a part of the larger transcription export (TREX) complex that couples messenger RNA processing and export. Additionally, THOC3 plays a key role in many cellular mechanisms, such as in the pathogenesis of cancer and neurodegenerative diseases (PMID: 36674977). THOC3 has 2 isoforms with the molecular weights of 36 and 39 kDa.

Protocols

Product Specific Protocols
WB protocol for THOC3 antibody 11716-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols