TRIB3 Monoclonal antibody
TRIB3 Monoclonal Antibody for WB,ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, Mouse, Rat and More (2)
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
2C10C7
Cat no : 66702-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
| Positive WB detected in | HT-29 cells, MCF-7 cells, rat liver tissue, mouse hepatocytes, DU 145 cells, LNCaP cells, PC-3 cells, HUVEC cells, HepG2 cells, L02 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:10000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 2 publications below |
Product Information
66702-1-Ig targets TRIB3 in WB, ELISA applications and shows reactivity with Human, Mouse, Rat samples.
| Tested Reactivity | Human, Mouse, Rat |
| Cited Reactivity | human, mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | TRIB3 fusion protein Ag25776 |
| Full Name | tribbles homolog 3 (Drosophila) |
| Calculated Molecular Weight | 358 aa, 40 kDa |
| Observed Molecular Weight | 40-45 kDa |
| GenBank Accession Number | BC027484 |
| Gene Symbol | TRIB3 |
| Gene ID (NCBI) | 57761 |
| RRID | AB_2882055 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
TRIB3 is a pseudokinase molecule that affects a number of cellular functions. TRIB3 has been reported to be highly activated in the presence of a variety of stressors, including the deprivation of neurotrophic factors, hypoxia, and ER stress.TRIB3 protein is associated with a good prognosis in human breast cancer patients, possibly due to the fact that TRIB3 is involved in hypoxia tolerance.(PMID: 21704407). TRIB3 protein predicted molecular weights is approximately 39~45 kDa.(PMID: 31191318, PMID: 24414038, PMID: 31578236).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for TRIB3 antibody 66702-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
JCI Insight Mitochondrial and NAD+ metabolism predict recovery from acute kidney injury in a diverse mouse population | ||
