XRCC4 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 15817-1-AP

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Freight/Packing

Con: 42 μg/150 μl

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Species specificity:
human, rat

Positive WB detected in:
HepG2 cells, COLO 320 cells, HepG2 cells

Positive IP detected in:
HepG2 cells

Positive IHC detected in:
human breast cancer tissue, human breast cancer tissue, rat small intestine tissue, rat testis tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
X-ray repair complementing defective repair in Chinese hamster cells 4

Calculated molecular weight:
310aa,35 kDa

Observed molecular weight:
55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
XRCC4

Synonyms
DNA repair protein XRCC4, XRCC4
Background

There are at least two pathways for eukaryotes to repair DNA double-strand breaks: homologous recombination and nonhomologous end joining(NHEJ). XRCC4 is one of the core machiney of NHEJ that requied for double-strand break repair and V(D)J recombination. The DNA ligase IV(LIG4)-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4.


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