phospho-RCC1(Ser12) Antibody 0 Publications

Mouse Monoclonal| Catalog number: 60089-1-Ig |CloneNo.: 5G9D8

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Freight/Packing

Con: 105 μg/150 μl

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Tested Applications

Applications:
ELISA
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Species specificity:
human, mouse

Recommended dilution:

Product Information


Source:
Mouse

Purification method:
Caprylic acid/ammonium sulfate precipitation

Isotype:
IgG3

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
peptide

Full name:
regulator of chromosome condensation 1

Calculated molecular weight:
48 kDa

Observed molecular weight:
47 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
RCC1

Synonyms
Cell cycle regulatory protein, CHC1, RCC1, RCC1 I
Background

CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a mouse monoclonal antibody raised against human phospho-CHC1(Ser12) antigen.


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