HDAC5-specific Monoklonaler Antikörper
HDAC5-specific Monoklonal Antikörper für ELISA
Wirt / Isotyp
Maus / IgG1
Getestete Reaktivität
human
Anwendung
ELISA
Konjugation
Unkonjugiert
CloneNo.
2A8C6
Kat-Nr. : 60157-1-Ig
Synonyme
Geprüfte Anwendungen
Produktinformation
60157-1-Ig bindet in ELISA HDAC5-specific und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Maus / IgG1 |
| Klonalität | Monoklonal |
| Typ | Antikörper |
| Immunogen | Peptid |
| Vollständiger Name | histone deacetylase 5 |
| Berechnetes Molekulargewicht | 122 kDa |
| GenBank-Zugangsnummer | BC051824 |
| Gene symbol | HDAC5 |
| Gene ID (NCBI) | 10014 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-G-Reinigung |
| Lagerungspuffer | PBS with 0.02% sodium azide and 50% glycerol |
| Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Histone acetylation and deacetylation alternately exposes and occludes DNA to transcription factors. At least 4 classes of HDAC were identified. HDAC5 is a class II HDAC. HDAC5 responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC5 is involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, HDAC5 shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. This antibody is a mouse monoclonal antibody raised against a peptide mapping within human HDAC5.
