ABCD1 Antibody
Rabbit Polyclonal
Catalog number: 11159-1-AP
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Applications
| Tested applications | ELISA, WB, IHC, IP |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | human brain tissue, HeLa cells |
| Positive IHC detected in | human lung cancer |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
IP result of anti-ABCD1 (11159-1-AP for IP and Detection) with Mouse liver tissue lysate.
human brain tissue were subjected to SDS PAGE followed by western blot with 11159-1-AP(ABCD1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human lung cancer using 11159-1-AP(ABCD1 Antibody) at Dilution 1:50 (under 10x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | ABCD1 fusion protein ag1635 | Full name | ATP-binding cassette, sub-family D (ALD), member 1 |
|
Calculated molecular weight |
745aa,83kd |
Observed molecular
weight |
75kd |
|
GenBank accession number |
BC025358 | Gene ID (NCBI) | 215 |
| Gene symbol | ABCD1 | Synonyms | ABC42; ALD; ALDP; AMN |
Background
ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex. |
