ACADL Antibody
Rabbit Polyclonal
Catalog number: 17442-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | |
| Species specificity | human, mouse; other species not tested. |
| Cited species | |
| Positive WB detected in | mouse kidney tissue, HEK-293 cells, HeLa cells, HepG2 cells, NIH/3T3 cells |
| Positive IHC detected in | human kidney |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with 17442-1-AP(ACADL Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney using 17442-1-AP(ACADL Antibody) at Dilution 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human kidney using 17442-1-AP(ACADL Antibody) at Dilution 1:50 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | ACADL fusion protein ag11530 | Full name | acyl-Coenzyme A dehydrogenase, long chain |
|
Calculated molecular weight |
430aa,48kd |
Observed molecular
weight |
45-48 kDa |
|
GenBank accession number |
BC039063 | Gene ID (NCBI) | 33 |
| Gene symbol | ACADL | Synonyms | ACAD4; FLJ94052; LCAD |
Background
ACADL(Long-chain specific acyl-CoA dehydrogenase, mitochondrial) is also named as LCAD and belongs to the acyl-CoA dehydrogenase family.It catalyzes the first reaction of the mitochondrial β-oxidation of fatty acids and is synthesized in the cytosol as a precursor that is larger than its mature from. The size difference between the precursor and mature rat LCAD has been estimated to be 3 kDa on the basis of SDS-PAGE(PMID:1774065).Defects in ACADL are a cause of acyl-CoA dehydrogenase very long-chain deficiency (ACADVLD).This antibody is specific to ACADL. |
