ACE2 Antibody
Rabbit Polyclonal
Catalog number: 21115-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | mouse kidney tissue, human skeletal muscle tissue |
| Recommended dilution | WB: 1:1000-1:10000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with 21115-1-AP(ACE2 Antibody) at dilution of 1:2000
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | ACE2 fusion protein ag15455 | Full name | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 |
|
Calculated molecular weight |
805aa,92kd |
Observed molecular
weight |
90-110kd |
|
GenBank accession number |
BC048094 | Gene ID (NCBI) | 59272 |
| Gene symbol | ACE2 | Synonyms | ACEH; DKFZp434A014 |
Background
ACE2 contains a potential 17-amino acid N-terminal signal peptide and a putative 22-amino acid C-terminal membrane anchor. It is the only known mammalian homologue of the zinc-metallopeptidase angiotensin-converting enzyme (ACE), a critical regulator of the reninangiotensin system.ACE2 has a more restricted tissue distribution than ACE, being found predominantly in the heart, kidneys, and testes although low levels have been detected in a variety of tissues(PMID:15983030). It can be N-Deglycosylation(PMID:16166094).It has 2 isoforms produced by alternative splicing.This antibody is specific to ACE2. |
