AEBP2 Antibody
Rabbit Polyclonal
Catalog number: 11232-2-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | ChIP, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | mouse |
| Positive WB detected in | human testis tissue |
| Recommended dilution | WB: 1:200-1:1000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
human testis tissue were subjected to SDS PAGE followed by western blot with 11232-2-AP(AEBP2 Antibody) at dilution of 1:300
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | AEBP2 fusion protein ag1756 | Full name | AE binding protein 2 |
|
Calculated molecular weight |
33kd,54KD |
Observed molecular
weight |
52kd |
|
GenBank accession number |
BC015624 | Gene ID (NCBI) | 121536 |
| Gene symbol | AEBP2 | Synonyms | MGC17922 |
Background
AEBP2 belongs to the AEBP2/jing C2H2-type zinc-finger family. It is a DNA-binding transcriptional repressor. AEBP2 is a zinc finger protein that has been shown to interact with the mammalian Polycomb Repression Complex 2 (PRC2). It may interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3. AEBP2 is an evolutionarily well-conserved gene that is found in the animals ranging from flying insects to mammals. (PMID:19293275) The antibody recognizes adult-specific larger form (52 kDa) and the embryo-specific smaller form (31 kDa). |
