AHR Antibody
Rabbit Polyclonal
Catalog number: 17840-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human; other species not tested. |
| Cited species | |
| Positive WB detected in | MCF7 cells, HEK-293 cells, NIH/3T3 cells, PC-3 cells |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
MCF7 cells were subjected to SDS PAGE followed by western blot with 17840-1-AP(AHR Antibody) at dilution of 1:500
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | AHR fusion protein ag12193 | Full name | aryl hydrocarbon receptor |
|
Calculated molecular weight |
848aa,96kd |
Observed molecular
weight |
105kd |
|
GenBank accession number |
BC070080 | Gene ID (NCBI) | 196 |
| Gene symbol | AHR | Synonyms | bHLHe76 |
Background
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has been largely regarded as a mediator of xenobiotic metabolism [PMID:18483242]. It plays a part role in physiologic activities, including attenuation of the acute phase response, cytokine signaling, T helper (TH)17 immune cell differentiation, modulation of NF-κB activity, and regulation of hormonal signaling [PMID:20423157,18540824]. It also mediates transcription factor sequestering away from a gene promoter or tethering of the AhR to a transcription factor on a promoter. |
