ALDOC Antibody
Rabbit Polyclonal
Catalog number: 14884-1-AP
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Applications
| Tested applications | ELISA, WB, IF |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | mouse cerebellum tissue, human heart tissue, K-562 cells, mouse brain tissue |
| Positive IF detected in | HepG2 cells |
| Recommended dilution | WB: 1:500-1:5000 IF: 1:20-1:50 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 14884-1-AP(ALDOC Antibody) at dilution of 1:1200
Immunofluorescent analysis of HepG2 cells, using ALDOC antibody 14884-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | ALDOC fusion protein ag6659 | Full name | aldolase C, fructose-bisphosphate |
|
Calculated molecular weight |
39kd |
Observed molecular
weight |
40kd |
|
GenBank accession number |
BC003613 | Gene ID (NCBI) | 230 |
| Gene symbol | ALDOC | Synonyms | ALDC |
Background
Fructose-bisphosphate aldolase C (ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097). This antibody is specific to ALDOC. |
