ARG1 AntibodyRabbit Polyclonal
|Tested applications||ELISA, WB, IHC, IP|
|Species specificity||human, mouse, rat; other species not tested.|
|Positive WB detected in||human colon tissue, human heart tissue, human liver tissue, mouse heart tissue, mouse liver tissue|
|Positive IHC detected in||human liver|
|Recommended dilution||WB: 1:500-1:5000|
IP = Immunoprecipitation
- IP result of anti-ARG1 (16001-1-AP for IP and Detection) with mouse liver tissue lysate.
- human colon tissue were subjected to SDS PAGE followed by western blot with 16001-1-AP(ARG1 Antibody) at dilution of 1:1000
- Immunohistochemistry of paraffin-embedded human liver using 16001-1-AP(ARG1 Antibody) at Dilution 1:50 (under 10x lens)
- Immunohistochemistry of paraffin-embedded human liver using 16001-1-AP(ARG1 Antibody) at Dilution 1:50 (under 40x lens)
|Source||Rabbit||Purification method||Antigen affinity purification|
|Isotype||IgG||Storage||PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.|
|Immunogen||ARG1 fusion protein ag8595||Full name||arginase, liver|
|BC005321||Gene ID (NCBI)||383|
ARG1(Arginase-1) belongs to the arginase family. Hepatic arginase 1 is closely associated with alternative macrophage activation(PMID:12098359) and Arg1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia (ARGIN).This antibody is specific to ARG1.