ARG1 Antibody
Rabbit Polyclonal
Catalog number: 16001-1-AP
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Applications
| Tested applications | ELISA, WB, IHC, IP |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | human colon tissue, human heart tissue, human liver tissue, mouse heart tissue, mouse liver tissue |
| Positive IHC detected in | human liver |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
IP result of anti-ARG1 (16001-1-AP for IP and Detection) with mouse liver tissue lysate.
human colon tissue were subjected to SDS PAGE followed by western blot with 16001-1-AP(ARG1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver using 16001-1-AP(ARG1 Antibody) at Dilution 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human liver using 16001-1-AP(ARG1 Antibody) at Dilution 1:50 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | ARG1 fusion protein ag8595 | Full name | arginase, liver |
|
Calculated molecular weight |
236aa,25kd;322aa,35kd |
Observed molecular
weight |
35-36kd |
|
GenBank accession number |
BC005321 | Gene ID (NCBI) | 383 |
| Gene symbol | ARG1 | Synonyms |
Background
ARG1(Arginase-1) belongs to the arginase family. Hepatic arginase 1 is closely associated with alternative macrophage activation(PMID:12098359) and Arg1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia (ARGIN).This antibody is specific to ARG1. |
