ARL13B AntibodyRabbit Polyclonal
|Tested applications||ELISA, WB, IF, IP|
|Cited applications||IF, WB|
|Species specificity||human, mouse, rat; other species not tested.|
|Cited species||human, mouse|
|Positive WB detected in||mouse liver tissue, mouse kidney tissue, NIH/3T3 cells, L02 cells|
|Recommended dilution||WB: 1:500-1:5000|
IP = Immunoprecipitation
- IF result of anti-ARL13B(17711-1-AP) in NIH3T3 cell by Dr. Sudipto.
- IP result of anti-ARL13B (17711-1-AP for IP and Detection) with Lo2 cell.
- IF result from Dr. Corbit, Kevin. anti-ARL13B(17711-1-AP) mark the cilium of Mouse embryonic fibroblasts.
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 17711-1-AP(ARL13B Antibody) at dilution of 1:1000
|Source||Rabbit||Purification method||Antigen affinity purification|
|Isotype||IgG||Storage||PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.|
|Immunogen||ARL13B fusion protein ag12015||Full name||ADP-ribosylation factor-like 13B|
|BC094725||Gene ID (NCBI)||200894|
|Gene symbol||ARL13B||Synonyms||ARL2L1; DKFZp686E2075; DKFZp686L2472; DKFZp686M2074; DKFZp761H079; JBTS8; MGC120611; MGC120612|
ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870). ARL13B can be used to mark the cilia (PMID:22072986).