ARL13B Antibody
Rabbit Polyclonal
Catalog number: 17711-1-AP
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Applications
| Tested applications | ELISA, WB, IF, IP |
| Cited applications | IF, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, mouse |
| Positive WB detected in | mouse liver tissue, mouse kidney tissue, NIH/3T3 cells, L02 cells |
| Recommended dilution | WB: 1:500-1:5000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
IF result of anti-ARL13B(17711-1-AP) in NIH3T3 cell by Dr. Sudipto.
IP result of anti-ARL13B (17711-1-AP for IP and Detection) with Lo2 cell.
IF result from Dr. Corbit, Kevin. anti-ARL13B(17711-1-AP) mark the cilium of Mouse embryonic fibroblasts.
mouse liver tissue were subjected to SDS PAGE followed by western blot with 17711-1-AP(ARL13B Antibody) at dilution of 1:1000
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | ARL13B fusion protein ag12015 | Full name | ADP-ribosylation factor-like 13B |
|
Calculated molecular weight |
321aa,37kd |
Observed molecular
weight |
40-48kd,66kd |
|
GenBank accession number |
BC094725 | Gene ID (NCBI) | 200894 |
| Gene symbol | ARL13B | Synonyms | ARL2L1; DKFZp686E2075; DKFZp686L2472; DKFZp686M2074; DKFZp761H079; JBTS8; MGC120611; MGC120612 |
Background
ARL13B, also named as ARL2L1, is a small ciliary G protein of the Ras superfamily. Localized in the cilia, it is required for cilium biogenesis and sonic hedgehog signaling. Defects in ARL13B are the cause of Joubert syndrome (JS) which is an autosomal recessive disorder characterized by a distinctive cerebellar malformation (PMID: 19906870). ARL13B can be used to mark the cilia (PMID:22072986). |
