AZGP1 Antibody
Rabbit Polyclonal
Catalog number: 13399-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IHC, WB |
| Species specificity | human; other species not tested. |
| Cited species | human |
| Positive WB detected in | PC-3 cells, MCF7 cells |
| Positive IHC detected in | human breast cancer |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
PC-3 cells were subjected to SDS PAGE followed by western blot with 13399-1-AP(AZGP1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human breast cancer using 13399-1-AP(AZGP1 Antibody) at Dilution 1:100 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | AZGP1 fusion protein ag4232 | Full name | alpha-2-glycoprotein 1, zinc-binding |
|
Calculated molecular weight |
298aa,34kd |
Observed molecular
weight |
41kd or 33kd |
|
GenBank accession number |
BC033830 | Gene ID (NCBI) | 563 |
| Gene symbol | AZGP1 | Synonyms | ZA2G; ZAG |
Background
Zinc-alpha-2-glycoprotein (AZGP1) is a soluble protein normally found in body fluids, functions as a lipid mobilizing factor (PMID: 19188554). It is known to be expressed in the secretory epithelia of the liver, lung, breast, GI tract and sweat glands, sharing significant structural similarity with the class I major histocompatibility complex (MHC) antigens (PMID: 3422450). AZGP1 is involved in carcinogenesis and differentiation. Altered expression of AZGP1 has been reported in breast cancer, prostate cancer and lung adenocarcinoma, hepatocellular carcinoma, pancreatic carcinoma and oral tumors (PMID: 22625427). |
