BCL11A Antibody
Rabbit Polyclonal
| Tested applications | ELISA, IHC |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive IHC detected in | human gliomas |
| Recommended dilution | IHC: 1:20-1:200 |
IP = Immunoprecipitation
Immunohistochemistry of paraffin-embedded human gliomas using 11613-1-AP(BCL11A Antibody) at Dilution 1:50 (under 10x lens)
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
| Immunogen | BCL11A fusion protein ag2187 | Full name | B-cell CLL/lymphoma 11A (zinc finger protein) |
|
Calculated molecular weight |
835aa,91kd |
Observed molecular
weight |
|
|
GenBank accession number |
BC021098 | Gene ID (NCBI) | 53335 |
| Gene symbol | BCL11A | Synonyms | BCL11A-L; BCL11A-S; BCL11A-XL; CTIP1; EVI9; FLJ10173; FLJ34997; HBFQTL5; KIAA1809; ZNF856 |
B-CELL CLL/LYMPHOMA 11A(BCL11A)is a highly conserved zinc finger gene. It acts as a myeloid and B-cell proto-oncogene, and may play key roles in leukemogenesis and hematopoiesis. It is an essential factor in lymphopoiesis, and required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1. It is also involved in lymphoid malignancies through translocation or amplification events. It has recently been shown that BCL11A expression is inversely correlated with γ globin expression.(PMID:21156846). This is a rabbit polyclonal antibody raised against part chain of N-terminal BCL11A of human origin. There are three isoforms of BCL11A: isoform1(773aa), isoform2(486aa) and isoform3(239aa) |
