BCL2 Antibody
Mouse Monoclonal
Catalog number: 60178-1-Ig
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human; other species not tested. |
| Cited species | |
| Positive WB detected in | Jurkat cells |
| Recommended dilution | WB: 1:500-1:5000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
Jurkat cells were subjected to SDS PAGE followed by western blot with 60178-1-Ig(BCL2 Antibody) at dilution of 1:1000
Product Information
| Source | Mouse | Purification method | Caprylic acid/ammonium sulfate precipitation |
| Isotype | IgG2b | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | BCL2 fusion protein ag3508 | Full name | B-cell CLL/lymphoma 2 |
|
Calculated molecular weight |
26kd |
Observed molecular
weight |
26kd |
|
GenBank accession number |
BC027258 | Gene ID (NCBI) | 596 |
| Gene symbol | BCL2 | Synonyms | Bcl-2 |
Background
BCL2 belongs to the Bcl-2 family. It is a suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. BCL2 regulates cell death by controlling the mitochondrial membrane permeability. It appears to function in a feedback loop system with caspases. BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). |
