BMP4 Antibody
Rabbit Polyclonal
Catalog number: 12492-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, mouse |
| Positive WB detected in | COLO 320 cells, human skeletal muscle tissue, mouse heart tissue |
| Positive IHC detected in | human lung |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
COLO 320 cells were subjected to SDS PAGE followed by western blot with 12492-1-AP(BMP4 Antibody) at dilution of 1:1500
Immunohistochemistry of paraffin-embedded human lung using 12492-1-AP(BMP4 Antibody) at Dilution 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human lung using 12492-1-AP(BMP4 Antibody) at Dilution 1:50 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | BMP4 fusion protein ag3191 | Full name | bone morphogenetic protein 4 |
|
Calculated molecular weight |
47kd |
Observed molecular
weight |
54kd |
|
GenBank accession number |
BC020546 | Gene ID (NCBI) | 652 |
| Gene symbol | BMP4 | Synonyms | BMP2B; BMP2B1; MCOPS6; ZYME |
Background
BMP4, also named as BMP2B and DVR4, belongs to the TGF-beta family. BMPs have been shown to promote astroglial differentiation both in vitro and in vivo. BMP4 have been shown to be components of serum and are thought to be responsible for this differentiation. are expressed mainly in neurons, with minimal expression detected in astrocytes and oligodendrocytes. |
