BRCA2 Antibody
Rabbit Polyclonal
Catalog number: 19791-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human; other species not tested. |
| Cited species | |
| Positive WB detected in | human brain tissue, HeLa cells |
| Recommended dilution | WB: 1:200-1:1000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
human brain tissue were subjected to SDS PAGE followed by western blot with 19791-1-AP(BRCA2 Antibody) at dilution of 1:300
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Peptide | Full name | breast cancer 2, early onset |
|
Calculated molecular weight |
384kd |
Observed molecular
weight |
384kd |
|
GenBank accession number |
NM_000059 | Gene ID (NCBI) | 675 |
| Gene symbol | BRCA2 | Synonyms | BRCC2; BROVCA2; FACD; FAD; FAD1; FANCB; FANCD; FANCD1 |
Background
BRCA2, also named as FACD and FANCD1, is involved in double-strand break repair and/or homologous recombination. BRCA2 may participate in S phase checkpoint activation. Defects in BRCA2 are a cause of genetic susceptibility to breast cancer (BC) which also called susceptibility to familial breast-ovarian cancer type 2 (BROVCA2). |
