BRSK1 Antibody
Rabbit Polyclonal
Catalog number: 12673-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | rat |
| Positive WB detected in | mouse brain tissue, human brain tissue |
| Positive IHC detected in | human ovary tumor |
| Recommended dilution | WB: 1:200-1:2000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with 12673-1-AP(BRSK1 Antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human ovary tumor using 12673-1-AP(BRSK1 Antibody) at Dilution 1:50 (under 10x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | BRSK1 fusion protein ag3357 | Full name | BR serine/threonine kinase 1 |
|
Calculated molecular weight |
87kd |
Observed molecular
weight |
85-90kd |
|
GenBank accession number |
BC016681 | Gene ID (NCBI) | 84446 |
| Gene symbol | BRSK1 | Synonyms | FLJ43009; KIAA1811 |
Background
BRSK1(Brain-specific serine/threonine-protein kinase 1) is also named as KIAA1811, SAD1, SADB and belongs to the SNF1 subfamily. BRSKs are crucial for establishing neuronal polarity, and BRSK1 has also been shown to regulate neurotransmitter release presynaptically. BRSK1 is a serine-threonine kinases specifically expressed in the brain, and activated by LKB1-mediated phosphorylation of a threonine residue at their T-loop. (PMID:22020259). It has 3 isoforms produced by alternative splicing. This antibody is specific to BRSK1. |
