BVES Antibody
Rabbit Polyclonal
Catalog number: 12920-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IHC |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human |
| Positive WB detected in | mouse skeletal muscle tissue |
| Positive IHC detected in | human ovary tumor |
| Recommended dilution | WB: 1:200-1:2000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 12920-1-AP(BVES Antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human ovary tumor using 12920-1-AP(BVES Antibody) at Dilution 1:100 (under 10x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | BVES fusion protein ag3593 | Full name | blood vessel epicardial substance |
|
Calculated molecular weight |
360aa,41kd |
Observed molecular
weight |
41-70kd |
|
GenBank accession number |
BC034425 | Gene ID (NCBI) | 11149 |
| Gene symbol | BVES | Synonyms | HBVES; MGC42413; POP1; POPDC1 |
Background
BVES, also named as POP1, POPDC1 and hBVES, belongs to the popeye family. It is cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. It is involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells. It is also involved in striated muscle regeneration and repair and in the regulation of cell spreading. BVES is expressed in the progenitors of coronary artery smooth muscle cells as well as in differentiated smooth muscle cells. |
