CABC1 Antibody
Rabbit Polyclonal
Catalog number: 15528-1-AP
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Applications
| Tested applications | ELISA, WB, IF |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | human skeletal muscle tissue, human heart tissue |
| Positive IF detected in | Hela cells |
| Recommended dilution | WB: 1:1000-1:10000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 15528-1-AP(CABC1 Antibody) at dilution of 1:2000
Immunofluorescent analysis of Hela cells, using 15528-1-AP and Rhodamine-labeled goat anti-rabbit IgG (red).
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | CABC1 fusion protein ag7612 | Full name | chaperone, ABC1 activity of bc1 complex homolog (S. pombe) |
|
Calculated molecular weight |
72kd |
Observed molecular
weight |
60kd |
|
GenBank accession number |
BC005171 | Gene ID (NCBI) | 56997 |
| Gene symbol | CABC1 | Synonyms | ADCK3; ARCA2; COQ8; MGC4849; SCAR9 |
Background
CABC1 (Chaperone, ABC1 activity of bc1 complex homolog) is induced by the tumor suppressor p53 and is similar to the yeast ABC1, which is involved in an electron-transferring membrane protein complex in the respiratory chain. The CABC1 product was located in mitochondria, and may play an important role in mediating p53-inducible apoptosis. Four isoforms of CABC1 exist due to alternative splicing events. |
