CASP2 Antibody
Rabbit Polyclonal
Catalog number: 10436-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | mouse kidney tissue, HEK-293 cells, HeLa cells, HL-60 cells, Jurkat cells, mouse liver tissue |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse kidney tissue were subjected to SDS PAGE followed by western blot with 10436-1-AP(CASP2 Antibody) at dilution of 1:500
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | CASP2 fusion protein ag0694 | Full name | caspase 2, apoptosis-related cysteine peptidase |
|
Calculated molecular weight |
452aa,51kd |
Observed molecular
weight |
51kd |
|
GenBank accession number |
BC002427 | Gene ID (NCBI) | 835 |
| Gene symbol | CASP2 | Synonyms | CASP-2; ICH-1L; ICH-1L/1S; ICH1; NEDD2 |
Background
CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).This antibody is specific to CASP2. |
