CDCA4 Antibody
Rabbit Polyclonal
Catalog number: 11625-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human; other species not tested. |
| Cited species | |
| Positive WB detected in | HeLa cells, HEK-293 cells |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
HeLa cells were subjected to SDS PAGE followed by western blot with 11625-1-AP(CDCA4 Antibody) at dilution of 1:500
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | CDCA4 fusion protein ag2214 | Full name | cell division cycle associated 4 |
|
Calculated molecular weight |
241aa,26kd |
Observed molecular
weight |
33kd |
|
GenBank accession number |
BC025263 | Gene ID (NCBI) | 55038 |
| Gene symbol | CDCA4 | Synonyms | FLJ20764; FLJ52878; HEPP; MGC19517; SEI-3/HEPP |
Background
TRIP-Br proteins are a set of proteins with the potential to function in both transcriptional control and cell cycle regulation [PMID:18572021]. CECA4 is a member of TRIP-br family, based on its homologous sequence motifs including SERTA and a PHD-bromo-binding site which interacts with a series of bromodomain containing transcriptional cofactors[PMID:17141982]. When activated by E2F, CDCA4 consequently functions as a suppressor of E2F-responsive promoters to participate the regulation of cell proliferation through the E2F/pRb pathway [PMID:16098148]. |
