COLEC11 Antibody
Rabbit Polyclonal
Catalog number: 15269-1-AP
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Applications
| Tested applications | ELISA, WB, IF |
| Cited applications | IF, IHC |
| Species specificity | human, mouse, rat, zebrafish; other species not tested. |
| Cited species | Mouse |
| Positive WB detected in | mouse liver tissue |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
IF result(confocal image) of CL-K1 in ATCD5 cell show Golgi localization from Prof. Philip L. Beales.
mouse liver tissue were subjected to SDS PAGE followed by western blot with 15269-1-AP(COLEC11 Antibody) at dilution of 1:800
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | COLEC11 fusion protein ag7374 | Full name | collectin sub-family member 11 |
|
Calculated molecular weight |
29kd |
Observed molecular
weight |
34kd |
|
GenBank accession number |
BC000078 | Gene ID (NCBI) | 78989 |
| Gene symbol | COLEC11 | Synonyms | CL-K1-I; CL-K1-II; CL-K1-IIa; CL-K1-IIb; CLK1; DKFZp686N1868; MGC3279 |
Background
COLEC11, also named as CL-K1 and Collectin-11, belongs to the COLEC10/COLEC11 family. It is a lectin that binds to various sugars: fucose > mannose. It does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. COLEC11 binds to LPS. COLEC11 and MASP1 are two genes in the lectin complement pathway, they are mutated in 3MC syndrome, implicating this diverse inflammation-chemotaxis cascade in the etiology of human developmental disorders. COLEC11 serves as a guidance cue for neural crest cell migration.(PMID:21258343) |
