CYP2C8 Antibody
Rabbit Polyclonal
Catalog number: 16546-1-AP
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Applications
| Tested applications | ELISA, IHC |
| Cited applications | |
| Species specificity | human; other species not tested. |
| Cited species | |
| Positive IHC detected in | human liver |
| Recommended dilution | IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
Immunohistochemistry of paraffin-embedded human liver using 16546-1-AP(CYP2C8 Antibody) at Dilution 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human liver using 16546-1-AP(CYP2C8 Antibody) at Dilution 1:50 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | CYP2C8 fusion protein ag9898 | Full name | cytochrome P450, family 2, subfamily C, polypeptide 8 |
|
Calculated molecular weight |
490aa,56kd |
Observed molecular
weight |
|
|
GenBank accession number |
BC020596 | Gene ID (NCBI) | 1558 |
| Gene symbol | CYP2C8 | Synonyms | CPC8; MP-12/MP-20 |
Background
CYP2C8(Cytochrome P450 2C8) is also named as CYPIIC8, cytochrome P450 IIC2, cytochrome P450 MP-12, cytochrome P450 MP-20, cytochrome P450 form 1 and S-mephenytoin 4-hydroxylase. It belongs to the cytochrome P450 family. It is a monooxygenase involved in an NADPH-dependent electron transport pathway and a hepatic drug-metabolizing enzymes that oxidizes therapeutic drugs such as taxol and cerivastatin and endobiotics such as retinoic acid and arachidonic acid. It has 2 isoforms produced by alternative splicing. This antibody is specific to CYP2C8. |
