CYP4F11 Antibody
Rabbit Polyclonal
Catalog number: 12286-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | ChIP, WB |
| Species specificity | human; other species not tested. |
| Cited species | human |
| Positive WB detected in | human liver tissue, human kidney tissue |
| Positive IHC detected in | human liver cancer |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
human liver tissue were subjected to SDS PAGE followed by western blot with 12286-1-AP(CYP4F11 Antibody) at dilution of 1:1200
Immunohistochemistry of paraffin-embedded human liver cancer using 12286-1-AP(CYP4F11 Antibody) at Dilution 1:100 (under 10x lens)
Immunohistochemistry of paraffin-embedded human liver cancer using 12286-1-AP(CYP4F11 Antibody) at Dilution 1:100 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | CYP4F11 fusion protein ag2906 | Full name | cytochrome P450, family 4, subfamily F, polypeptide 11 |
|
Calculated molecular weight |
524aa,60kd |
Observed molecular
weight |
57kd |
|
GenBank accession number |
BC016853 | Gene ID (NCBI) | 57834 |
| Gene symbol | CYP4F11 | Synonyms |
Background
CYP4F11, also named as CYPIVF11, belongs to the cytochrome P450 family. It is the lone CYP4F/A enzyme that effectively oxidized 3-hydroxypalmitate. It is the predominant catalyst of this fatty acid oxidation reaction in human liver. CYP4F11 is one of the primary human epidermal keratinocytes. It is positively regulated by multiple signaling pathways in HaCaT keratinocytes, including RXR and JNK signaling pathways. (PMID:19812349) |
