DDC Antibody
Rabbit Polyclonal
Catalog number: 10166-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | IF, IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, mouse |
| Positive WB detected in | mouse brain tissue, mouse kidney tissue |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse brain tissue were subjected to SDS PAGE followed by western blot with 10166-1-AP(DDC Antibody) at dilution of 1:800
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | DDC fusion protein ag0219 | Full name | dopa decarboxylase (aromatic L-amino acid decarboxylase) |
|
Calculated molecular weight |
54kd |
Observed molecular
weight |
48-50 kDa |
|
GenBank accession number |
BC008366 | Gene ID (NCBI) | 1644 |
| Gene symbol | DDC | Synonyms | AADC |
Background
Aromatic-L-amino-acid decarboxylase belongs to the pyridoxal-dependent aminotransferase superfamily.DDC catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.DDC is the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD).Researches showed that Ddc is only one of the enzymes in the biosynthetic pathways for bioamines and catecholamines. |
