DHRS3 Antibody
Rabbit Polyclonal
| Tested applications | ELISA, WB |
| Cited applications | IF, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human |
| Positive WB detected in | A375 cells |
| Recommended dilution | WB: 1:200-1:2000 |
IP = Immunoprecipitation
A375 cells were subjected to SDS PAGE followed by western blot with 15393-1-AP(DHRS3 Antibody) at dilution of 1:500
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
| Immunogen | DHRS3 fusion protein ag7589 | Full name | dehydrogenase/reductase (SDR family) member 3 |
|
Calculated molecular weight |
34kd |
Observed molecular
weight |
34kd |
|
GenBank accession number |
BC002730 | Gene ID (NCBI) | 9249 |
| Gene symbol | DHRS3 | Synonyms | RDH17; Rsdr1; SDR1; SDR16C1; retSDR1 |
DHRS3(Short-chain dehydrogenase/reductase 3) is also named as retSDR1,DD83.1 and belongs to the short-chain dehydrogenases/reductases (SDR) family. It catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH. It is detected high levels of expression in fetal kidney, liver, and lung and in adult heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea, spinal cord and lower levels in skeletal muscle, intestine, and lymph node. retSDR1 is barely detectable in adrenals, brain, thymus, and hematopoietic tissues(PMID:11861404). retSDR1 may play a more general role in retinol metabolism since its expression was observed in many fetal and adult tissues(PMID:20543567). This antibody is specific to DHRS3. |
