Product Information
15483-1-AP targets DIDO1 in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | DIDO1 fusion protein Ag7826 Predict reactive species |
| Full Name | death inducer-obliterator 1 |
| Calculated Molecular Weight | 244 kDa |
| GenBank Accession Number | BC004237 |
| Gene Symbol | DIDO1 |
| Gene ID (NCBI) | 11083 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q9BTC0 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
DIDO1, also named as DATF-1, C20orf158, DATF1, KIAA0333 and DIO-1, is a putative transcription factor, weakly pro-apoptotic when overexpressed. It is a tumor suppressor. In mice, DIDO1 is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. The human DIDO1 is similar to the mouse gene and therefore is thought to be involved in apoptosis. The immunogen of this antibody is the N-terminal of DIDO1. This antibody can recognize all the isoform of DATF1 (DIDO1,DIDO2,DIDO3 and a).
