EGLN1 Antibody
Rabbit Polyclonal
Catalog number: 19886-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | mouse heart tissue, HEK-293 cells, MCF7 cells, mouse brain tissue, mouse kidney tissue |
| Recommended dilution | WB: 1:500-1:5000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse heart tissue were subjected to SDS PAGE followed by western blot with 19886-1-AP(EGLN1 Antibody) at dilution of 1:1200
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | EGLN1 fusion protein ag13706 | Full name | egl nine homolog 1 (C. elegans) |
|
Calculated molecular weight |
426aa,46kd |
Observed molecular
weight |
46kd |
|
GenBank accession number |
BC005369 | Gene ID (NCBI) | 54583 |
| Gene symbol | EGLN1 | Synonyms | C1orf12; DKFZp761F179; ECYT3; HIFPH2; HPH2; PHD2; SM-20; SM20; ZMYND6 |
Background
EGLN1(Egl nine homolog 1) is also named as HIF-PH2,HPH-2,PHD2.It is the most important isozyme under normoxia and, through regulating the stability of HIF1, involved in various hypoxia-influenced processes such as angiogenesis in retinal and cardiac functionality. EGLN1 plays a critical role in regulating HIF levels in EPO-producing cells in humans(PMID:16407130).Defects in EGLN1 are the cause of familial erythrocytosis type 3 (ECYT3).This antibody is specific to EGLN1. |
