ELL Antibody
Rabbit Polyclonal
Catalog number: 51044-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | WB |
| Species specificity | human, mouse; other species not tested. |
| Cited species | human |
| Positive WB detected in | HeLa cells, HEK-293 cells, HL-60 cells, mouse testis tissue |
| Positive IHC detected in | human ovary tumor |
| Recommended dilution | WB: 1:200-1:2000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
HeLa cells were subjected to SDS PAGE followed by western blot with 51044-1-AP(ELL Antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human ovary tumor using 51044-1-AP(ELL Antibody) at Dilution 1:50 (under 10x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | ELL fusion protein ag0617 | Full name | elongation factor RNA polymerase II |
|
Calculated molecular weight |
500aa,68kd |
Observed molecular
weight |
68-80kd |
|
GenBank accession number |
BC049195 | Gene ID (NCBI) | 8178 |
| Gene symbol | ELL | Synonyms | C19orf17; DKFZp434I1916; ELL1; MEN |
Background
ELL is an elongation factor that inrecase the catalytic rate of RNA polymerase II transcription via suppressing transient pausing by the polymerase at multiple sites along the DNA. Also it's the second elongation factor to be involved in oncogenesis which is a transcription factor regulated by the product of the von Hippel-Lindau tumor suppressor. There are two transcirpts variants in mRNA level, one is 4.4kb transcript and the other is 2.8kb transcript. |
