FAH Antibody
Rabbit Polyclonal
Catalog number: 14928-1-AP
Ask a question about this product click here
Loading price...
Applications
| Tested applications | ELISA, WB |
| Cited applications | WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human |
| Positive WB detected in | mouse liver tissue, human liver tissue |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with 14928-1-AP(FAH Antibody) at dilution of 1:500
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | FAH fusion protein ag6704 | Full name | fumarylacetoacetate hydrolase (fumarylacetoacetase) |
|
Calculated molecular weight |
46kd |
Observed molecular
weight |
40-45kd |
|
GenBank accession number |
BC002527 | Gene ID (NCBI) | 2184 |
| Gene symbol | FAH | Synonyms |
Background
FAH is also named as FAA(fumarylacetoacetase), the last enzyme in tyrosine degradation, functionally important in the liver and kidney(PMID:8473520). FAH is a metabolic enzyme catalyzing the last step of tyrosine and phenylalanine catabolism: the hydrolysis of fumarylacetoacetate into acetoacetate and fumarate. In humans, deficiency of this activity is associated with the metabolic disease hereditary tyrosinaemia type I, which is also known as hepatorenal tyrosinaemia(PMID:17768357). This antibody is specific to FAH. |
