FECH Antibody
Rabbit Polyclonal
Catalog number: 14466-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, rat |
| Positive WB detected in | human heart tissue, HeLa cells, HepG2 cells, human liver tissue, K-562 cells |
| Recommended dilution | WB: 1:500-1:5000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
human heart tissue were subjected to SDS PAGE followed by western blot with 14466-1-AP(FECH Antibody) at dilution of 1:1000
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | FECH fusion protein ag5814 | Full name | ferrochelatase (protoporphyria) |
|
Calculated molecular weight |
48kd |
Observed molecular
weight |
46kd |
|
GenBank accession number |
BC039841 | Gene ID (NCBI) | 2235 |
| Gene symbol | FECH | Synonyms | EPP; FCE |
Background
FECH(ferrochelatase, mitochondrial ) is also named as heme synthase, protoheme ferro-lyase and belongs to the ferrochelatase family. It is a homodimeric (86 kDa) mitochondrial membrane-associated enzyme that catalyzes the insertion of ferrous iron into protoporphyrin to form heme(PMID:11175906). It has 2 isoforms produced by alternative splicing and the full length protein has a transit peptide with 54 amino acids. This antibody is specific to FECH. |
