FHL1 Antibody
Rabbit Polyclonal
Catalog number: 10991-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | ChIP, CoIP, IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, mouse |
| Positive WB detected in | human brain tissue, mouse skeletal muscle tissue, mouse colon tissue |
| Positive IHC detected in | human ovary tumor |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
human brain tissue were subjected to SDS PAGE followed by western blot with 10991-1-AP(FHL1 Antibody) at dilution of 1:1200
Immunohistochemistry of paraffin-embedded human ovary tumor using 10991-1-AP(FHL1 Antibody) at Dilution 1:100 (under 10x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | FHL1 fusion protein ag1448 | Full name | four and a half LIM domains 1 |
|
Calculated molecular weight |
32kd |
Observed molecular
weight |
32kd |
|
GenBank accession number |
BC010998 | Gene ID (NCBI) | 2273 |
| Gene symbol | FHL1 | Synonyms | FHL1B; FLH1A; KYO-T; MGC111107; SLIM1; XMPMA; bA535K18.1 |
Background
Four-and-a-half LIM domains 1 (FHL1), a member of the FHL protein family, which composed of FHL 1, 2, 3, 4 and ACT (activator of CREM), and characterized by an N-terminal half LIM domain followed by four complete LIM domains. FHL1 may contribute to sarcomere synthesis, assembly and biomechanical stress sensing. FHL1 is also a methylation-silenced tumor-suppressor gene on chromosome X in gastrointestinal cancers, which contributes to the formation of an epigenetic field for cancerization. FHL1(10991-1-AP) is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. This is a rabbit polyantibody raised against full length of human FHL1. |
