FHL3 Antibody
Rabbit Polyclonal
Catalog number: 11028-2-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human |
| Positive WB detected in | K-562 cells, mouse ovary tissue |
| Positive IHC detected in | human ovary tumor |
| Recommended dilution | WB: 1:200-1:2000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
K-562 cells were subjected to SDS PAGE followed by western blot with 11028-2-AP(FHL3 Antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human ovary tumor using 11028-2-AP(FHL3 Antibody) at Dilution 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human ovary tumor using 11028-2-AP(FHL3 Antibody) at Dilution 1:50 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | FHL3 fusion protein ag1495 | Full name | four and a half LIM domains 3 |
|
Calculated molecular weight |
31kd |
Observed molecular
weight |
34kd |
|
GenBank accession number |
BC011697 | Gene ID (NCBI) | 2275 |
| Gene symbol | FHL3 | Synonyms | MGC19547; MGC23614; MGC8696; SLIM2 |
Background
Four and a half LIM domain (FHL) protein 3 is a member of the FHL protein family that has roles in the regulation of signal transduction, survival, cell adhesion, and mobility. It also involves in the development and progression of liver cancer. The FHL proteins have been shown to regulate a variety of transcription factors, including SMAD proteins, β-catenin, SRF, AP-1, NFAT, FOXO1, MyoD, and the androgen receptor. Beside, the FHL proteins may involve in muscle growth and differentiation. |
