FOXM1 Antibody
Rabbit Polyclonal
| Tested applications | ELISA, WB |
| Cited applications | IHC |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human |
| Positive WB detected in | mouse thymus tissue, mouse spleen tissue, mouse testis tissue, mouse colon tissue, L02 cells |
| Recommended dilution | WB: 1:500-1:5000 |
IP = Immunoprecipitation
mouse thymus tissue were subjected to SDS PAGE followed by western blot with 13147-1-AP(FOXM1 Antibody) at dilution of 1:1000
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
| Immunogen | FOXM1 fusion protein ag3729 | Full name | forkhead box M1 |
|
Calculated molecular weight |
83kd |
Observed molecular
weight |
110kd |
|
GenBank accession number |
BC006192 | Gene ID (NCBI) | 2305 |
| Gene symbol | FOXM1 | Synonyms | FKHL16; FOXM1B; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TGT3; TRIDENT |
Forkhead box M1 (FOXM1), also named HNF-3, HFH-11 or Trident, belongs to a superfamily of Fox transcription factors. FOXM1 is strongly associated with cell proliferation, it plays a important role in cell cycle progression by regulating both G1/S and G2/M phases, it is also involved in DNA damage repair, angiogenesis, apoptosis and tissue regeneration. Recently, crucial roles of this transcription factor were found in the development and progression of many cancers including colorectal, lung, prostate, liver and breast cancer. FOXM1 levels are significantly higher and associated with tumor grade in most human tumors, rendering it a potential target of cancer diagnosis and therapies. Catalog#13147-1-AP is rabbit polyclonal antibody raised against C-terminal of human FOXM1. And this antibody can recognize three kinds of FOXM1,FOXM1-pp(~95-110kDa), FOXM1-B(isoform2,~83kDa) and FOXM1A(isoform4, ~90kDa) |
