GAMT Antibody
Rabbit Polyclonal
Catalog number: 10880-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IHC |
| Species specificity | human, mouse, rat, zebrafish; other species not tested. |
| Cited species | zebrafish |
| Positive WB detected in | mouse liver tissue, HEK-293 cells, human brain tissue, human heart tissue, mouse brain tissue, mouse heart tissue, rat liver tissue |
| Positive IHC detected in | human prostate cancer |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:10-1:100 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
mouse liver tissue were subjected to SDS PAGE followed by western blot with 10880-1-AP(GAMT Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human prostate cancer using 10880-1-AP(GAMT Antibody) at Dilution 1:10 (under 25x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | GAMT fusion protein ag1327 | Full name | guanidinoacetate N-methyltransferase |
|
Calculated molecular weight |
26kd |
Observed molecular
weight |
26kd |
|
GenBank accession number |
BC016760 | Gene ID (NCBI) | 2593 |
| Gene symbol | GAMT | Synonyms | PIG2; TP53I2 |
Background
GAMT converts the latter to creatine with S-adenosylmethionine as the methyl donor. GAMT was induced in human and mouse cells in response to genotoxic and metabolic stress. GAMT was required for p53-dependent upregulation of creatine biosynthesis, fatty acid oxidation, and apoptosis in response to glucose deprivation. |
