GFER Antibody
Rabbit Polyclonal
Catalog number: 11293-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IF, IHC, WB |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human, mouse |
| Positive WB detected in | A375 cells, A431 cells, mouse liver tissue |
| Positive IHC detected in | human colon cancer |
| Recommended dilution | WB: 1:200-1:2000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
A375 cells were subjected to SDS PAGE followed by western blot with 11293-1-AP(GFER Antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human colon cancer using 11293-1-AP(GFER Antibody) at Dilution 1:100 (under 10x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | GFER fusion protein ag1840 | Full name | growth factor, augmenter of liver regeneration |
|
Calculated molecular weight |
15kd,23kd |
Observed molecular
weight |
30kd |
|
GenBank accession number |
BC028348 | Gene ID (NCBI) | 2671 |
| Gene symbol | GFER | Synonyms | ALR; ERV1; HERV1; HPO; HPO1; HPO2; HSS |
Background
GFER(FAD-linked sulfhydryl oxidase) is also named as ALR, HERV1, HPO. It plays an important role in the disulfide relay system (DRS) in human mitochondria.The GFER gene codes for 2 distinct isoforms that are probably synthesized from the same mRNA with the use of different initiation codons. The long isoform (205 amino acids, 23 kD) is located mainly in the mitochondrial intermembrane space and exists under nonreducing and nondenaturing conditions as a homodimer and a heterodimer. The shorter isoform (125 amino acids, 15 kD), which lacks 80 amino acids at its N terminus compared to the longer isoform, is present predominantly in the nucleus(PMID:19409522).This antibody is specific to GFER. |
