Product Information
10339-1-AP targets GIT2 in ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag0321 Product name: Recombinant human GIT2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 254-462 aa of BC001379 Sequence: DSSLDLSELAKAAKKKLQSLSNHLFEELAMDMYDEVDRRETDAVWLATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQGSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKSLDSDLSDGPVTVQEFMEVKNALVASEAKIQQLMKVNNNLSDELRIMQ Predict reactive species |
| Full Name | G protein-coupled receptor kinase interacting ArfGAP 2 |
| Calculated Molecular Weight | 95 kDa |
| GenBank Accession Number | BC001379 |
| Gene Symbol | GIT2 |
| Gene ID (NCBI) | 9815 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q14161 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
G protein-coupled receptor kinase-interacting protein 2(GIT2) is a signaling scaffold protein involved in the regulation of membrane trafficking, cytoskeletal structure, and G protein-coupled receptor internalization. It belongs to the GIT fmaily that has been shown to involve in regrlating emotional function, vascular development and mitochondrial biogenesis. Also GIT protein may have role in focal adhesion dynamics, cell migration and directing the spatial localization of signaling molecules such as MEK1 and ERK1/2.
