GLB1 Antibody
Rabbit Polyclonal
Catalog number: 15518-1-AP
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Applications
| Tested applications | ELISA, WB, IF |
| Cited applications | WB |
| Species specificity | human, mouse; other species not tested. |
| Cited species | human, mouse |
| Positive WB detected in | SH-SY5Y cells |
| Positive IF detected in | Hela cells |
| Recommended dilution | WB: 1:200-1:2000 IF: 1:20-1:50 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 15518-1-AP(GLB1 Antibody) at dilution of 1:600
Immunofluorescent analysis of Hela cells, using GLB1 antibody 15518-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | GLB1 fusion protein ag7792 | Full name | galactosidase, beta 1 |
|
Calculated molecular weight |
76kd |
Observed molecular
weight |
67kd |
|
GenBank accession number |
BC007493 | Gene ID (NCBI) | 2720 |
| Gene symbol | GLB1 | Synonyms | EBP; ELNR1 |
Background
GLB1(Beta-galactosidase) is also named as ELNR1, Lactase.It cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans.This protein is identical to the elastin-binding protein (EBP), a major component of the nonintegrin cell surface receptor complex expressed in fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types.Defects in GLB1 are the cause of GM1-gangliosidosis type 1 (GM1G1) ,GM1-gangliosidosis type 2 (GM1G2),GM1-gangliosidosis type 3 (GM1G3) and mucopolysaccharidosis type 4B (MPS4B).This protein is specific to GLB1. |
