GLI3-Specific Antibody
Rabbit Polyclonal
Catalog number: 19949-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | human placenta tissue, mouse lung tissue |
| Recommended dilution | WB: 1:200-1:1000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
human placenta tissue were subjected to SDS PAGE followed by western blot with 19949-1-AP(GLI3-Specific Antibody) at dilution of 1:400
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | Peptide | Full name | GLI family zinc finger 3 |
|
Calculated molecular weight |
170kd |
Observed molecular
weight |
230kd,83-86kd |
|
GenBank accession number |
NM_000168 | Gene ID (NCBI) | 2737 |
| Gene symbol | GLI3 | Synonyms | ACLS; GCPS; PAP-A; PAPA; PAPA1; PAPB; PHS; PPDIV |
Background
GLI3 belongs to the GLI C2H2-type zinc-finger protein family. GLI3 plays a role in limb and brain development. GLI3 is implicated in the transduction of SHH signal. Defects in GLI3 are the cause of Greig cephalo-poly-syndactyly syndrome (GCPS). Defects in GLI3 are a cause of Pallister-Hall syndrome (PHS). Defects in GLI3 are a cause of type A1/B postaxial polydactyly (PAPA1/PAPB). Defects in GLI3 are a cause of type IV preaxial polydactyly. Defects in GLI3 are the cause of acrocallosal syndrome (ACS). The antibody is specific to GLI3. |
