GRWD1 Antibody
Rabbit Polyclonal
Catalog number: 10354-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | HEK-293 cells |
| Positive IHC detected in | human prostate cancer |
| Recommended dilution | WB: 1:200-1:2000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with 10354-1-AP(GRWD1 Antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human prostate cancer using 10354-1-AP(GRWD1 Antibody) at Dilution 1:100 (under 25x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | GRWD1 fusion protein ag0367 | Full name | glutamate-rich WD repeat containing 1 |
|
Calculated molecular weight |
49kd |
Observed molecular
weight |
49kd |
|
GenBank accession number |
BC002440 | Gene ID (NCBI) | 83743 |
| Gene symbol | GRWD1 | Synonyms | GRWD; KIAA1942; RRB1; WDR28 |
Background
WD-repeat proteins are a class of functionally divergent molecules that cooperate with other proteins to regulate cellular processes. WD-repeat proteins have been implicated in a variety of cellular functions that are mostly regulatory in nature, including cytoskeleton organization, vesicular fusion, pre-mRNA splicing, and cell cycle regulation. WD-repeat-containing protein designated glutamate-rich WD repeat (GRWD1) is a component of the 50S and 80S preribosomal complexes and plays a role in ribosome biogenesis and during myeloid differentiation its levels are regulated. [PMID:15885502] |
