HNRNPH1 Antibody
Rabbit Polyclonal
Catalog number: 14774-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | IHC |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | human |
| Positive WB detected in | mouse brain tissue, HeLa cells |
| Positive IHC detected in | human cervical cancer |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:20-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
WB result from Dr. Corbit Kevin. Mouse embryonic stem cell were used to test the antibody 14774-1-AP.
mouse brain tissue were subjected to SDS PAGE followed by western blot with 14774-1-AP(HNRNPH1 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human cervical cancer using 14774-1-AP(HNRNPH1 Antibody) at Dilution 1:50 (under 10x lens)
Immunohistochemistry of paraffin-embedded human cervical cancer using 14774-1-AP(HNRNPH1 Antibody) at Dilution 1:50 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | HNRNPH1 fusion protein ag6506 | Full name | heterogeneous nuclear ribonucleoprotein H1 (H) |
|
Calculated molecular weight |
49kd |
Observed molecular
weight |
49kd |
|
GenBank accession number |
BC001348 | Gene ID (NCBI) | 3187 |
| Gene symbol | HNRNPH1 | Synonyms | DKFZp686A15170; HNRPH; HNRPH1; hnRNPH |
Background
The heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. HNRNPH1 is one component of hnRNP complex and mediates pre-mRNA alternative splicing regulation [PMID:11003644]. Together with CUGBP1, it inhibits IR pre-mRNA exon 11 inclusion in myoblast [PMID: 16946708]. |
