HSF1 Antibody
Rabbit Polyclonal
Catalog number: 16107-1-AP
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Applications
| Tested applications | ELISA, WB |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | K-562 cells |
| Recommended dilution | WB: 1:200-1:2000 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
K-562 cells were subjected to SDS PAGE followed by western blot with 16107-1-AP(HSF1 Antibody) at dilution of 1:800
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | HSF1 fusion protein ag9023 | Full name | heat shock transcription factor 1 |
|
Calculated molecular weight |
529aa,57kd |
Observed molecular
weight |
68-80kd |
|
GenBank accession number |
BC014638 | Gene ID (NCBI) | 3297 |
| Gene symbol | HSF1 | Synonyms | HSTF1 |
Background
HSF1 belongs to heat-shock transcription factor that activate heat-shock response genes under conditions of heat or other stresses. Also, HSF1 has linked with oogenesis, spermatogenesis, and placental development. It can activate AKT and inactivate JNK and CASP3 to protect cardiomyocytes from death. And it has a role in the regulation of life span and establishs a role for SIRT1 in protein homeostasis and heat-shock response. |
