IKZF2 Antibody
Rabbit Polyclonal
Catalog number: 13554-1-AP
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Applications
| Tested applications | ELISA, WB, IHC |
| Cited applications | |
| Species specificity | human, mouse, rat; other species not tested. |
| Cited species | |
| Positive WB detected in | human placenta tissue |
| Positive IHC detected in | human lymphoma |
| Recommended dilution | WB: 1:500-1:5000 IHC: 1:50-1:200 |
Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
IP = Immunoprecipitation
Images
human placenta tissue were subjected to SDS PAGE followed by western blot with 13554-1-AP(IKZF2 Antibody) at dilution of 1:1200
Immunohistochemistry of paraffin-embedded human lymphoma using 13554-1-AP(IKZF2 Antibody) at Dilution 1:100 (under 10x lens)
Immunohistochemistry of paraffin-embedded human lymphoma using 13554-1-AP(IKZF2 Antibody) at Dilution 1:100 (under 40x lens)
Product Information
| Source | Rabbit | Purification method | Antigen affinity purification |
| Isotype | IgG | Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen | IKZF2 fusion protein ag4357 | Full name | IKAROS family zinc finger 2 (Helios) |
|
Calculated molecular weight |
500aa,57kd |
Observed molecular
weight |
65kd |
|
GenBank accession number |
BC028936 | Gene ID (NCBI) | 22807 |
| Gene symbol | IKZF2 | Synonyms | HELIOS; MGC34330; ZNF1A2; ZNFN1A2 |
Background
Ikaros DNA-binding proteins, characterized by two highly conserved zinc finger domains that mediate DNA (N-terminal domain) and protein binding (C-terminal domain), consists of 5 members and one of them is IKZF2 [PMID:1439790]. IKZF2's expression is associated with T cell activation and cellular division and is suggested a suitable marker to distinguish natural and induced Treg [PMID:21918685]. |
