Tested Applications
| Positive WB detected in | HEK-293 cells, HepG2 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 2 publications below |
Product Information
15648-1-AP targets IL-17RC in WB, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag8190 Product name: Recombinant human IL-17RC protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-350 aa of BC006411 Sequence: MPVPWFLLSLALGRSPVVLSLERLVGPQDATHCSPGLSCRLWDSDILCLPGDIVPAPGPVLAPTHLQTELVLRCQKETDCDLCLRVAVHLAVHGHWEEPEDEEKFGGAADSGVEEPRNASLQAQVVLSFQAYPTARCVLLEVQVPAALVQFGQSVGSVVYDCFEAALGSEVRIWSYTQPRYEKELNHTQQLPALPWLNVSADGDNVHLVLNVSEEQHFGLSLYWNQVQGPPKPRWHKNLTGPQIITLNHTDLVPCLCIQVWPLEPDSVRTNICPFREDPRAHQNLWQAARLRLLTLQSWLLDAPCSLPAEAALCWRAPGGDPCQPLVPPLSWENVTVDKVLEFPLLKGHP Predict reactive species |
| Full Name | interleukin 17 receptor C |
| Calculated Molecular Weight | 791aa,86 kDa; 538aa,59 kDa |
| Observed Molecular Weight | 45-50 kDa |
| GenBank Accession Number | BC006411 |
| Gene Symbol | IL-17RC |
| Gene ID (NCBI) | 84818 |
| RRID | AB_2296016 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q8NAC3 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
The IL-17 family has five receptors: IL-17RA (or IL-17R), IL-17RB (or IL-17Rh1), IL-17RC (or IL-17RL), IL-17RD and IL-17RE. IL-17RC is a 720-amino acid type I transmembrane protein with a 20-amino acid signal peptide, a 447-amino acid N-terminal extracellular domain, a 21-amino acid hydrophobic α-helical transmembrane domain, and a 232-amino acid intracellular domain(PMID: 18928529). IL17RC is widely expressed in nonleukocyte tissues and forms a heteromeric receptor for IL17 with IL17R(PMID: 16785495).
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for IL-17RC antibody 15648-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Sci Total Environ Interleukin-17A knockout or self-recovery alleviated autoimmune reaction induced by fluoride in mouse testis |
